Relationship between patients’ pre-operative anxiety level and administration of anxiolytic premedication

Pre-operative anxiety and use of anxiolytic medication

Authors

DOI:

https://doi.org/10.26550/2209-1092.1391

Keywords:

assessing acute pre-operative anxiety, use of anxiolytic premedication, role of perioperative nursing

Abstract

Objective: To evaluate the relationship between the patient’s reported level of pre-operative anxiety, the anaesthesiologist’s assessment of the patients’ anxiety level and the administration of anxiolytic premedication in the immediate pre-operative period.

Methods: Patients' pre-operative anxiety level was self-assessed using a simple visual analog scale (0 = no anxiety to 10 = severe anxiety) in the pre-operative holding area. The anaesthesiologist independently visually assessed the patient’s level of anxiety on a similar 0 to 10 anxiety rating scale at the time of their pre-operative interview. Immediately after this, the anaesthesiologist decided whether to administer an anxiolytic medication prior to the patient entering the operating room. 

Results: Based on the anxiety scores reported by patients on the numeric analog scale, 58% (n=171) reported no-to-low levels of anxiety (scores ≤3) and 42% (n=122) reported moderate-to-high levels of anxiety (scores ≥4). According to the observational assessment by the anaesthesiologists, 70% of the patients were assigned an anxiety score ≤3 and 30% were assigned an anxiety score ≥4.  Overall, 188 out of the 293 patients (64%) received a parenteral anxiolytic premedication. However, only 50% (61/122) of the patients reporting moderate-to-high levels of anxiety received an anxiolytic medication prior to entering the operating room. Surprisingly, 74% (127/171) of the patients reporting little or no anxiety were administered an anxiolytic drug. Interestingly, there was no significant difference in the average anxiety scores of patients who did or did not receive anxiolytic premedication (3.6±2.6 vs. 3.0±2.2, p= 0.11). 

Conclusions:  These data suggest there is poor correlation between the patient’s reported level of pre-operative anxiety and the administration of anxiolytic medication. A more targeted approach to administering anxiolytic premedication based on the patient’s self-reported anxiety level in the pre-operative holding area would lead to more rationale use of anxiolytic medication prior to the patient entering the operating room.

Author Biographies

Professor, https://orcid.org/0000-0003-2275-819X

UT Southwestern Medical Center, Dallas, TX (retired)
White Mountain Institute, The Sea Ranch, CA, USA (President)

Dr., https://orcid.org/0000-0002-2825-5182

Department of Anesthesiology, Cedars-Sinai Medical Center, Los Angeles, CA, USA

Professor, https://orcid.org/0000-0002-3645-7972

  1. Department of Anesthesiology, Cedars-Sinai Medical Center, Los Angeles, CA, USA
  2. David Geffen School of Medicine-UCLA, Charles R. Drew University of Medicine and Science, Los Angeles, CA, USA
  3. Department of Anesthesiology, IU Health Bloomington, Indiana University, IN

Dr., https://orcid.org/0000-0003-4248-1546

Department of Mathematical Sciences, Michigan Technological University. Houghton, MI, USA

Professor, https://orcid.org/0000-0003-1970-4756

Department of Psychiatry, Cedars-Sinai Medical Center, Los Angeles, CA, USA

Dr.

Department of Anesthesiology, Cedars-Sinai Medical Center, Los Angeles, CA, USA

Professor

  1. Department of Anesthesiology, Cedars-Sinai Medical Center, Los Angeles, CA, USA
  2. Department of Anesthesiology, Keck School of Medicine. Los Angeles, CA, USA 

Dr.

  1. Department of Anesthesiology, Cedars-Sinai Medical Center, Los Angeles, CA, USA
  2. Department of Anesthesiology and Critical Care, Saint Louis University School of medicine, Saint Louis, MO, USA

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Published

22-03-2026

How to Cite

White , P. F., Elvir Lazo, O. L., Yumul , R., Zhang , X., So, L., IsHak , W. W., … Sadeghipour , H. (2026). Relationship between patients’ pre-operative anxiety level and administration of anxiolytic premedication: Pre-operative anxiety and use of anxiolytic medication . Journal of Perioperative Nursing, 39(1), 20–28. https://doi.org/10.26550/2209-1092.1391

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